The building of the former Jewish school was erected in the years 1821-1823. On November 28, 1823, the first service was held in the small synagogue. The building was subject to numerous modifications and it was only in the middle of the 19th century that it received today’s shape. In addition to the place for the service and for the young people to study, there was an apartment for the Rabbi and a chamber of meetings of the authorities of the Jewish kehilla. During the Second World War, the Jewish school housed the seat of the Jewish Council (Judenrat) and the Order Service (Ordnungdienst). After the war, the first meeting of Płock Jews was held in the building, during which a Jewish Committee was established, headed by Dawid Lichtensztajn. From 1950, the building housed the seat of the Gerszon Dua Clothing Workshop Cooperative in Płock. In 1955, the building at Kwiatka street was passed to the Municipal Management of Residential Buildings in Płock. In 1960, at the request of the Finance Department, the Presidium of the Provincial National Council in Warsaw established a mortgage register for the property. In 1962, the building was entered into the register of monuments. Since 2013, the Museum of Mazovian Jews has been operating in the building. Preserved from the old interior furnishings, there is a Torah ark from the first half of the 19th century. Subject to conservation in 1998, in February 2015 it has returned to its place in the former synagogue.
In 2022, on the basis of a photo from the collection of the Ghetto Fighters’ House, two commemorative plaques that were once placed in the synagogue building at Kwiatka Street were reconstructed. The smaller plaque commemorated Aron Lajzer (Lesser) Byszofswerder (1834-1913), son of Icek and Ruchla, trader, owner of the Borzewo estate and the property at 11 Grodzka Street in Płock, who came from Dobrzyń on the Drwęca River. His wife was Tauba née Firszt, with whom he had four children: Sura Ruchla vel Zofia (born 1860), Icek Lemel vel Leopold (born 1865), Moszek Lejb (born 1867) and Estera Liba (born 1871). Aron Lajzer (Lesser) Byszofswerder died on April 27, 1913. After his death, his wife and children financed the installation of an electric lighting installation in the synagogue on Kwiatka Street to honor his memory. One of his sons – Leopold Byszofswerder, was a doctor of internal medicine and a neurologist (he graduated in Paris, in 1902 he received his doctorate after defending the thesis entitled “Contribution à l’etude de l’anatomie pathologique de la syringomyélie” and the title of doctor “cum eximia laude”). Similarly to his father, he was known for his philanthropic activities, he supported financially poor Jewish families, he collaborated with charity organizations in Płock.